ARAŞTIRMA

Yayınlar

2023 YILI YAYINLARI

1. İnsan diş pulpası kaynaklı mezenkimal kök hücrelerin meme kanseri kök hücreleri üzerine etkisi Gİ Yengin, ÖG Geyik, HA BAĞRIYANIK, Y Zeynep, G Öktem Ege Tıp Dergisi 62 (3), 396-405 

 2. β-hydroxybutyrate Does Not Influence Viability and Clonogenicity of A549 Lung Cancer Cells AB Özkaya, S Malcanlı, Ö Gönül Geyik Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 14 (2) 

3. Effects of phenolic compounds of colored wheats on colorectal cancer cell lines ÖG Geyik, ZH Tekin-Cakmak, VP Shamanin, S Karasu, IV Pototskaya, Sergey S Shepelev, Alexandr S Chursin, Alexey I Morgounov, Mustafa Yaman, Osman Sagdic, Hamit Köksel Quality Assurance and Safety of Crops & Foods 2023 

4. Mertk-expressıng macrophages promote the malıgnant features of cholangıocarcınoma cells M Pastore, OG Geyik, J Andersen, Monika Lewinska, Ana Lleo, Paolo Kunderfranco, Claudia Campani, Luca Di Tommaso, Claudia Piombo, Luca Vigano, Jamila Faivre, Chiara Raggi, Fabio Marra Hepatology 76, S187-S188 

5. Altinkaynak C, Haciosmanoglu E, Ekremoğlu M, Hacioglu M, Özdemir N., Anti-microbial, anti-oxidant and wound healing capabilities of Aloe vera-incorporated hybrid nanoflowers J. Biosci. Bioeng. 2023 doi.org/10.1016/j.jbiosc.2023.01.004 

6. Ahmet Melih Öten, Evren Atak, Banu Taktak Karaca, Sinem Fırtına & Aslı Kutlu (2023) Discussing the roles of proline and glycine from the perspective of cold adaptation in lipases and cellulases, Biocatalysis and Biotransformation, 41:4, 243-260, DOI: 10.1080/10242422.2022.2124111. 

7. Çapkın E, Kutlu A, Yüce M. Repurposing Fc gamma receptor I (FcγRI, CD64) for siteoriented monoclonal antibody capture: A proof-of-concept study for real-time detection of tumor necrosis factor-alpha (TNF -α). Heliyon. 2023 Aug 26;9(9):e19469. doi: 10.1016/j.heliyon.2023.e19469. 

8. GEYİK, C., GUMUS, Z. P., & YARARBAS, G. (2023). COMPOSITION ANALYSIS OF E-LIQUIDS AND THEIR EFFECTS ON HEALTHY LIVER AND PHARYNGEAL CARCINOMA CELL LINES. Trakya University Journal of Natural Sciences, 24(1), 21-29. https://doi.org/10.23902/trkjnat.1135237. 

9. Çelik, H., Caf, B.B., Geyik, C. et al. Enhancing urinalysis with smartphone and AI: a comprehensive review of point-of-care urinalysis and nutritional advice. Chem. Pap. (2023). https://doi.org/10.1007/s11696-023-03137-z. 

10. Dedeakayoğulları H, Valjakka J, Turunen O, Yilmazer B, Demir Ğ, Jänis J, Binay B. Application of reductive amination by heterologously expressed Thermomicrobium roseumL-alanine dehydrogenase to synthesize L-alanine derivatives. Enzyme Microb Technol. 2023 Sep;169:110265. doi: 10.1016/j.enzmictec.2023.110265. Epub 2023 May 24. 

11. Samir, N., Özerkan, D., Danışman-Kalındemirtaş, F. et al. Synthesis and Anticancerogenic Effect of New Generation Ruthenium-Based Nanoparticle from Homalothecium sericeum with Eco-Friendly Method. J Pharm Innov 18, 756–767 (2023). https://doi.org/10.1007/s12247-023-09725-6. 

12. Hamzaoğlu Canbolat K, Öncül M, Özel A, Alıcı Davutoğlu E, Kaymak D, Bulut H, Madazlı R. Oxidative stress and antioxidant status in threatened preterm labor. Arch Gynecol Obstet. 2023 Apr 1. doi: 10.1007/s00404-023-07023-7. Epub ahead of print. 

13. Kilic A, Ustunova S, Bulut H, Meral I. Pre and postnatal exposure to 900 MHz electromagnetic fields induce inflammation and oxidative stress, and alter renin-angiotensin system components differently in male and female offsprings. Life Sci. 2023 May 15;321:121627. doi: 10.1016/j.lfs.2023.121627. Epub 2023 Mar 28. 

14. J. Depciuch, W. Paja, K. Pancerz, Ö. Uzun, H. Bulut, N. Tarhan, Z. Guleken, J Raman Spectrosc 2023, 54(5), 501. https://doi.org/10.1002/jrs.6510. 

15. Danişman-Kalindemirtaş F, Özerkan D, Kariper İA, Bulut H. The Novel 5-Fluorouracil Loaded Ruthenium-based Nanocarriers Enhanced Anticancer and Apoptotic Efficiency while Reducing Multidrug Resistance in Colorectal Cancer Cells. J Fluoresc. 2023 May;33(3):1227-1236. doi: 10.1007/s10895-023-03180-9. Epub 2023 Feb 22. 

16. Kutlu E, Ozgen LT, Bulut H, Kocyigit A, Ustunova S, Hüseyinbas O, Torun E, Cesur Y. Investigation of irisin's role in pubertal onset physiology in female rats. Peptides. 2023 May;163:170976. doi: 10.1016/j.peptides.2023.170976. Epub 2023 Feb 14.

17. Depciuch J, Jakubczyk P, Paja W, Pancerz K, Wosiak A, Bahat PY, Toto ÖF, Bulut H, Guleken Z. Increased levels of nerve growth factor accompany oxidative load in recurrent pregnancy loss. Machine learning applied to FT-Raman spectra study. Bioprocess Biosyst Eng. 2023 Apr;46(4):599-609. doi: 10.1007/s00449-023-02847-8. Epub 2023 Jan 26. 

18. Taslidere, E., Esrefoglu, M., Tok, O., Taslidere, B., & Bulut, H.. (2022). Effects of melatonin on both testicular regeneration and recovery of spermatogenesis in busulfan-treated rats. Brazilian Journal of Pharmaceutical Sciences, 58, e20945. https://doi.org/10.1590/s2175- 97902022e20945. 

19. Yilmaz G, Bulut H, Ozden Omaygenc D, Akca A, Can E, Tuten N, Bestel A, Erdem B, Atmaca UO, Kara Y, Kaya E, Unsel M, Sahin AS, Salihoglu Z. Baseline serum vitamin A and vitamin C levels and their association with disease severity in COVID-19 patients. Acta Biomed. 2023 Feb 13;94(1):e2023007. doi: 10.23750/abm.v94i1.13655. 

20. K. Adacan, Z. Gokmen, R. Okan Akar, Z. Ozyıldız, H. Dinçer, D. Karakaş, E. Ulukaya, ChemistrySelect 2023, 8, e202301955. 

21. Genel ME, Adacan K, Selvi S, Kutucu DE, Uvez A, Armutak EI, Sengul A, Ulukaya E, Gurevin EG. Apoptosis-inducing, anti-angiogenic and anti-migratory effects of a dinuclear Pd(II) complex on breast cancer: A promising novel compound. Microvasc Res. 2024 Jan;151:104619. doi: 10.1016/j.mvr.2023.104619. Epub 2023 Oct 26. 

22. Samir, N., Özerkan, D., Danışman-Kalındemirtaş, F. et al. Synthesis and Anticancerogenic Effect of New Generation Ruthenium-Based Nanoparticle from Homalothecium sericeum with Eco-Friendly Method. J Pharm Innov 18, 756–767 (2023). https://doi.org/10.1007/s12247-023-09725-6. 

23. Icsel C, Yilmaz VT, Aygun M, Erkisa M, Ulukaya E. Water-soluble copper(II) 5- fluorouracil complexes bearing polypyridyl co-ligands: synthesis, structures and anticancer activity. Dalton Trans. 2023 May 30;52(21):7048-7058. doi: 10.1039/d3dt00363a. 

24. Bulut H, Tarhan N, Büyük M, Serin KR, Ulukaya E, Depciuch J, Parlinska-Wojtan M, Guleken Z. Assessment of Oxidative Stress Effects in Serum Determined by FT-IR Spectroscopy in Cholangiocarcinoma Patients. Biointerface Research in Applied Chemistry, 2023, 13(2);151. 

25. Karakas D, Erkisa M, Akar RO, Akman G, Senol EY, Ulukaya E. Targeting Periostin Expression Makes Pancreatic Cancer Spheroids More Vulnerable to Natural Killer Cells. Biomedicines. 2023 Jan 19;11(2):270. doi: 10.3390/biomedicines11020270. 

26. ERTÜRK, ELİF; AKGÜN, OĞUZHAN; YILDIZ, YAREN; KALKAN, PINAR; SALOMATINA, OKSANA V.; SALAKHUTDINOV, NARIMAN F.; ULUKAYA, ENGİN; and ARI, FERDA (2023) "Soloxolone methyl induces apoptosis and oxidative/ER stress in breast cancer cells and target cancer stem cell population," Turkish Journal of Biology: Vol. 47: No. 4, Article 4. https://doi.org/10.55730/1300-0152.2660 

27. Kiyan HT, Uvez A, Erkisa M, Ikitimur-Armutak EI, Yilmazer N, Esener OBB, Kutucu DE, Ustunova S, Ulukaya E, Ozturk AA, Gurel-Gurevin E. A Comparative Study on In vitro Anti-cancer and In vivo Anti-angiogenic Effects of TRPC Blockers Pyr-3 and SKF-96365. Letters in Drug Design and Discovery, 2023, 20(7); 957-64. 

28. ÖZYURT, RUMEYSA; ERKASAP, NİLÜFER; ÖZKURT, METE; ERKASAP, SERDAR MUSTAFA; DİMAS, KONSTANTİNOS; GÜNDOĞDU, AYŞE ÇAKIR; and ULUKAYA, ENGİN (2023) "Targeting of Notch, IL-1, and leptin has therapeutic potential in xenograft colorectal cancer," Turkish Journal of Biology: Vol. 47: No. 4, Article 7. https://doi.org/10.55730/1300-0152.2663.

2022 YILI YAYINLARI

1. Köse, M. E., Aydin, B., Geyik, C., Geyik, Ö. G., & Ulukaya, E. (2022). Effects of exosomes on major pathways promote tumor formation and progression. Current Molecular Medicine22(6), 491-505.

2. Özkaya, A. B., & Geyik, C. (2022). From viability to cell death: Claims with insufficient evidence in high-impact cell culture studies. PloS one17(2), e0250754.

3. Bulut, H., Teloğlu, E. Ş., Şentürk, H., Üstünova, S., Güleken, Z., & Selek, Ş. (2022). Çuha Çiçeği Ve Sarı Kantaron Yağlarının Multiple Skleroz Modeli Oluşturulmuş Farelerdeki Jak/Stat Sinyal Yolakları Üzerine Etkisi. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi24(2), 225-235.

 

4. Comba, C., Ozdemir, I. A., Demirayak, G., Erdogan, S. V., Demir, O., Yıldız, G. Ö., ... & Gungorduk, K. (2022). The effect of omentectomy on the blood levels of adipokines in obese patients with endometrial cancer. Obesity Research & Clinical Practice16(3), 242-248.

5. Can, E., Oğlak, S. C., Ölmez, F., & Bulut, H. (2022). Serum neutrophil gelatinase-associated lipocalin concentrations are significantly associated with the severity of COVID-19 in pregnant patients. Saudi medical journal43(6), 559-566.

6. Hamzaoğlu, K., Alıcı Davutoğlu, E., Bulut, H., & Madazli, R. (2022). Prediction of preterm delivery in threatened preterm labour with short cervical length. Journal of Obstetrics and Gynaecology, 1-6.

7. Guleken, Z., Bulut, H., Bulut, B., Paja, W., Parlinska-Wojtan, M., & Depciuch, J. (2022). Correlation between endometriomas volume and Raman spectra. Attempting to use Raman spectroscopy in the diagnosis of endometrioma. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy274, 121119.

8. Guleken, Z., Bulut, H., Bulut, B., Paja, W., Orzechowska, B., Parlinska-Wojtan, M., & Depciuch, J. (2022). Identification of polycystic ovary syndrome from blood serum using hormone levels via Raman spectroscopy and multivariate analysis. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy273, 121029.

9. Ustunova, S., Kilic, A., Bulut, H., Gurel-Gurevin, E., Eris, A. H., & Meral, I. (2022). Impaired memory by hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic fields is ameliorated by thymoquinone. Toxicological & Environmental Chemistry104(1), 176-193.

10. Utkusavas, A., Gurel Gurevin, E., Yilmazer, N., Uvez, A., Oztay, F., Bulut, H., ... & Armutak, E. I. (2022). Effects of combined administration of doxorubicin and chloroquine on lung pathology in mice with solid Ehrlich ascites carcinoma. Biotechnic & Histochemistry, 1-12.

11. Tüten, A., Tüten, N., Gök, K., Hamzaoglu, K., Bulut, H., Malik, E., & Guralp, O. (2022). Serum vasostatin-1 level is increased in women with preeclampsia. Zeitschrift für Geburtshilfe und Neonatologie.

12. Depciuch, J., Parlinska-Wojtan, M., Serin, K. R., Bulut, H., Ulukaya, E., Tarhan, N., & Guleken, Z. (2022). Differential of cholangiocarcinoma disease using Raman spectroscopy combined with multivariate analysis. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy272, 121006.

13. Gönül Geyik, Ö., Anichini, G., Ulukaya, E., Marra, F., & Raggi, C. (2022). DNA Damage Response Inhibitors in Cholangiocarcinoma: Current Progress and Perspectives. Cells11(9), 1463.

14. Pastore, M., Geyik, O. G., Andersen, J. B., Lewinska, M., Lleo, A., Kunderfranco, P., ... & Marra, F. (2022). Cross-talk between MerTK-expressing stromal cells and cholangiocarcinoma. Digestive and Liver Disease54, S5-S6.

15. Bozkurt, S., Unal, S., & Gumruk, F. (2022). First report of t (1; 9)(q21; q34) in Fanconi anemia as a preceeding chromosomal aberration before leukemia development.

16. Ekremoglu, M., Haciosmanoglu, E., Hacioglu, M., Altinkaynak, C., & Ozdemir, N. (2022). A novel wound healing agent with antimicrobial properties: BSA-inorganic hybrid nanoflowers.

17. Gerçek, Z., Yıldız, U., Ulukaya, E., & Akar, R. O. (2022). Synthesis, DNA binding and cytotoxic activity of newcopper (II) complexes of trisubstituted imidazoles. Pharmaceutical Chemistry Journal55(12), 1320-1328.

18. Yenenler-Kutlu, A., Arda, M., Atak, E., & Ulukaya, E. (2022). Identification of key genes and pathways for cholangiocarcinoma using an integrated bioinformatics analysis. International Journal of Medical Biochemistry5(3), 0-0.

19. Gerlevik, U., Saygı, C., Cangül, H., Kutlu, A., Çaralan, E. F., Topçu, Y., ... & Sezerman, O. U. (2022). Computational analysis of missense filamin-A variants, including the novel p. Arg484Gln variant of two brothers with periventricular nodular heterotopia. Plos one17(5), e0265400.

20. Öten M.A., Atak E., Taktak-Karaca, B., Fırtına, S., Kutlu, A. (2022) Discussing the roles of proline and glycine from the perspective of cold adaptation in lipases and cellulases. Biocatalysis & Biotransformation. Ahead of Print. Doi: 10.1080/10242422.2022.2124111

21. Turna, O., Uvez, A., Baykal, A., Sedef Develi, E., Diramali, M., Sonmez, K., ... & Ulukaya, E. (2022). Evidence for heterogeneity in response to treatment in mammary tumors of dogs as happens in humans. Veterinary Research Communications, 1-10.

22. Icsel, C., Yilmaz, V. T., Aygun, M., Erkisa, M., & Ulukaya, E. (2022). Novel 5-fluorouracil complexes of Zn (II) with pyridine-based ligands as potential anticancer agents. Dalton Transactions51(13), 5208-5217.

23. Savani, S., Onbasli, K., Gunduz, H., Aydındogan, E., Erkısa, M., Muti, A., ... & Kolemen, S. (2022). Development of a cysteine responsive chlorinated hemicyanine for image-guided dual phototherapy. Bioorganic Chemistry122, 105725.

24. Erkisa, M., Sariman, M., Geyik, O. G., Geyik, C. G., Stanojkovic, T., & Ulukaya, E. (2022). Natural products as a promising therapeutic strategy to target cancer stem cells. Current Medicinal Chemistry29(4), 741-783.

25. Onbasli, K., Erkısa, M., Demirci, G., Muti, A., Ulukaya, E., Sennaroglu, A., & Acar, H. Y. (2022). The improved killing of both androgen-dependent and independent prostate cancer cells by etoposide loaded SPIONs coupled with NIR irradiation. Biomaterials Science10(14), 3951-3962.

 

26. Ozturk, E. A., Ege, Z. R., Murat, S., Erdemir, G., Kuruca, S., Erkmen, Z. E., ... & Eroglu, M. S. (2022). Poly (L-lactic acid)/poly (ethylene oxide) based composite electrospun fibers loaded with magnesium-aluminum layered double hydroxide nanoparticles. International Journal of Biological Macromolecules217, 562-571.

27. Danışman-Kalındemirtaş, F., Kariper, İ. A., Erdemir, G., Sert, E., & Erdem-Kuruca, S. (2022). Evaluation of anticancer effects of carboplatin–gelatin nanoparticles in different sizes synthesized with newly self-assembly method by exposure to IR light. Scientific reports12(1), 1-11.

28. Özerkan, D., Erol, A., Altuner, E. M., Canlı, K., & Kuruca, D. S. (2022). Some bryophytes trigger cytotoxicity of stem cell-like population in 5-fluorouracil resistant colon cancer cells. Nutrition and Cancer74(3), 1012-1022.

 

29. Cevatemre, B., Ulukaya, E., Dere, E., Dilege, S., & Acilan, C. (2022). Pyruvate dehydrogenase contributes to drug resistance of lung cancer cells through epithelial mesenchymal transition. Frontiers in cell and developmental biology, 9, 3745.

 

30. Genel, M. E., Selvi, S., Yilmaz, I., Akar, R. O., Yaylim, I., ŞENGÜL, A., & Ulukaya, E. (2022). Differential Cytotoxic Activity of a New Cationic Pd (II) Coordination Compound with N4-Tetradentate Hybrid Ligand in Cancer Cell Lines. Experimed12(3), 188-201.

 

31. Erkısa Genel, M., (2022) A Comparative Study on In vitro Anti-cancer and In vivo Antiangiogenic Effects of TRPC Blockers Pyr-3 and SKF-96365. Letters in Drug Design & Discovery

 

32. Bildaci, Y. D., Bulut, H., Elcioglu, O. C., Gursu, M., & Kazancioglu, R. (2022). Alteration of inflammation marker levels with alfa keto analogs in diabetic rats. Nigerian Journal of Clinical Practice25(9), 1452-1456.

 

33. Guleken, Z., Bahat, P. Y., Toto, Ö. F., Bulut, H., Jakubczyk, P., Cebulski, J., ... & Depciuch, J. (2022). Blood serum lipid profiling may improve the management of recurrent miscarriage: a combination of machine learning of mid-infrared spectra and biochemical assays. Analytical and Bioanalytical Chemistry414(29-30), 8341-8352.

 

34. Can, E., Bakirci, I. T., Bulut, H., Guler, F. Y., & Cetin, A. (2022). Role of serum metalloproteinases 2 and 9 to assess the severity of COVID-19 in pregnant women: a prospective cross-sectional study. Ginekologia Polska.

 

35. Özden, H., Gömeç, M., Şahin, Y., Karaca, G., BULUT, H., & Kilitçi, A. (2022). The Healing Effect of Resveratrol and Platelet Rich Plasma in Corrosive Esophagitis Model in Rats. Cumhuriyet Medical Journal, 44(3).

 

36. Onsun, N., Akaslan, T. Ç., Sallahoglu, K., Gülcan, A. S., Bulut, H., & Yabacı, A. (2022). Effects of TNF inhibitors and an IL12/23 inhibitor on changes in body weight and adipokine levels in psoriasis patients: A 48-week comparative study. Journal of Dermatological Treatment, 33(3), 1727-1732.

 

37. Guleken, Z., Jakubczyk, P., Wiesław, P., Krzysztof, P., Bulut, H., Öten, E., ... & Tarhan, N. (2022). Characterization of Covid-19 infected pregnant women sera using laboratory indexes, vibrational spectroscopy, and machine learning classifications. Talanta, 237, 122916.

 

38. Tüten, N., Güralp, O., Gök, K., Hamzaoglu, K., Oner, Y. O., Makul, M., ... & Malik, E. (2022). Serum catestatin level is increased in women with preeclampsia. Journal of Obstetrics and Gynaecology, 42(1), 55-60.

 

39. Gerçek, Z., Yıldız, U., Akar, R. O., & Ulukay, E. (2022). Selective Cytotoxicity of Novel Copper (II) Complex on Colon Cancer Cell Lines. European Journal of Advanced Chemistry Research, 3(3), 45-54.

 

40. Polo, P. G., Çolak-Al, B., Sentürk, H., & Rafiqi, A. M. (2022). Gut bacteria after recovery from COVID-19: a pilot study. European Review for Medical and Pharmacological Sciences, 26(22), 8599-8611.

 

41. Geyik, C. , Gumus, Z. P. & Yararbas, G. (2023). COMPOSITION ANALYSIS OF ELIQUIDS AND THEIR EFFECTS ON HEALTHY LIVER AND PHARYNGEAL CARCINOMA CELL LINES . Trakya University Journal of Natural Sciences , (Online First Publications) , 0-0 . DOI: 10.23902/trkjnat.1135237

 

42. Pastore, M.,Geyik, OG.,Andersen, J.Lewinska, M.,Lleo, A.,(2022). Mertk-expressıng macrophages promote the malıgnant features of cholangıocarcınoma cells.76,S187- S188.

 

      2021 YILI YAYINLARI

 

1. Ozturk, S., Erkisa, M., Oran, S., Ulukaya, E., Celikler, S., & Ari, F. (2021). Lichens exerts an anti-proliferative effect on human breast and lung cancer cells through induction of apoptosis. Drug and chemical toxicology44(3), 259-267.

2. Erkisa, M., Ari, F., Büyükköroğlu, G., Şenel, B., Yilmaz, V. T., & Ulukaya, E. (2021). Preparation and Characterization of Palladium Derivate‐Loaded Micelle Formulation in Vitro as an Innovative Therapy Option against Non‐Small Cell Lung Cancer Cells. Chemistry & Biodiversity18(9), e2100402.

3. Aydinlik, S., Erkisa, M., Ari, F., Celikler, S., & Ulukaya, E. (2021). Palladium (II) complex enhances ROS-dependent apoptotic effects via autophagy inhibition and disruption of multiple signaling pathways in colorectal cancer cells. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents)21(10), 1284-1291.

 

4. Erkisa, M., Aztopal, N., Erturk, E., Ulukaya, E., Yilmaz, V. T., & Ari, F. (2021). Combination of histone deacetylase inhibitor with Cu (II) 5, 5-diethylbarbiturate complex induces apoptosis in breast cancer stem cells: a promising novel approach. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents)21(14), 1850-1860.

5. Hussein, M. A. M., Su, S., Ulag, S., Woźniak, A., Grinholc, M., Erdemir, G., ... & Megahed, M. (2021). Development and in vitro evaluation of biocompatible pla-based trilayer nanofibrous membranes for the delivery of nanoceria: a novel approach for diabetic wound healing. Polymers13(21), 3630.

6. Yeşiltepe, O., Çelik, E. G., Geyik, C., GÜMÜŞ, Z. P., Demirkol, D. O., Coşkunol, H., & Timur, S. (2021). Preparation of glutathione loaded nanoemulsions and testing of hepatoprotectiveactivity on THLE-2 cells. Turkish Journal of Chemistry45(2), 436-451.

7. Atak, E., Karaoğlu, D., Serttürk, S., Irmak, D. K., & Yenenler-Kutlu, A. (2021). Performing the comparative analysis to understand the functional roles of genes in different pathways of cardiomyopathy disease. Meta Gene30, 100975.

8. Aslan, T., Yenenler-Kutlu, A., Gerlevik, U., Aktuğlu Zeybek, A. Ç., Kıykım, E., Sezerman, O. U., & Birgul Iyison, N. (2021). Identifying and elucidating the roles of Y198N and Y204F mutations in the PAH enzyme through molecular dynamic simulations. Journal of Biomolecular Structure and Dynamics, 1-12.

9. Özerkan, D., Özsoy, N., Cebesoy, S., & Özer, Ç. (2021). Distribution of spleen connective tissue fibers in diabetic and vitamin C treated diabetic rats. Biotechnic & Histochemistry96(5), 347-353.

10. Ulukaya, E., Karakas, D., & Dimas, K. (2021). Tumor chemosensitivity assays are helpful for personalized Cytotoxic treatments in cancer patients. Medicina57(6), 636.

11. Karakas, D., & Ozpolat, B. (2021). The role of LncRNAs in translation. Non-coding RNA7(1), 16.

 

12. Guleken, Z., Jakubczyk, P., Wiesław, P., Krzysztof, P., Bulut, H., Öten, E., ... & Tarhan, N. (2022). Characterization of Covid-19 infected pregnant women sera using laboratory indexes, vibrational spectroscopy, and machine learning classifications. Talanta237, 122916.

13. Guleken, Z., Bulut, H., Depciuch, J., & Tarhan, N. (2022). Diagnosis of endometriosis using endometrioma volume and vibrational spectroscopy with multivariate methods as a noninvasive method. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy264, 120246.

14. Guleken, Z., Bulut, H., Bulut, B., & Depciuch, J. (2021). Assessment of the effect of endocrine abnormalities on biomacromolecules and lipids by FT-IR and biochemical assays as biomarker of metabolites in early Polycystic ovary syndrome women. Journal of Pharmaceutical and Biomedical Analysis204, 114250.

15. Ustunova, S., Haciosmanoglu, E., Bulut, H., Elibol, B., Kilic, A., Hekimoglu, R., ... & Meral, I. (2021). A low direct electrical signal attenuates oxidative stress and inflammation in septic rats. Plos one16(9), e0257177.

16. Tüten, N., Malik, E., Gök, K., Hamzaoglu, K., Makul, M., Öner, Y. Ö., ... & Güralp, O. (2021). Serum neprilysin levels are elevated in preeclampsia. Taiwanese Journal of Obstetrics and Gynecology60(5), 869-873.

17. Guleken, Z., Bulut, H., Gültekin, G. İ., Arıkan, S., Yaylım, İ., Hakan, M. T., ... & Depciuch, J. (2021). Assessment of structural protein expression by FTIR and biochemical assays as biomarkers of metabolites response in gastric and colon cancer. Talanta231, 122353.

 

18. Onsun, N., Akaslan, T. Ç., Sallahoglu, K., Gülcan, A. S., Bulut, H., & Yabacı, A. Effects of TNF inhibitors and an IL12/23 inhibitor on changes in body weight and adipokine levels in psoriasis patients: A 48-week comparative study. Journal of Dermatological Treatment, 2021,1-16.

19. Guleken, Z., Depciuch, J., Ege, H., İlbay, G., Kalkandelen, C., Ozbeyli, D., ... & Kuruca, S. E. (2021). Spectrochemical and biochemical assay comparison study of the healing effect of the Aloe vera and Hypericum perforatum loaded nanofiber dressings on diabetic wound. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy254, 119639.

20. Güralp, O., Gök, K., Tüten, N., Hamzaoglu, K., Makul, M., Oner, Y. O., ... & Tüten, A. (2021). Serum survivin is decreased in women with preeclampsia. Hypertension in Pregnancy40(2), 144-151.

21. Kilic, A., Ustunova, S., Elibol, B., Bulut, H., Meral, I., & Sahin, G. (2021). Angiotensin IV improves spatial memory in streptozotocin‑induced diabetic rats by reducing oxidative stress and altering BDNF levels. Acta Neurobiol Exp, 81.

22. Kilic, A., Ustunova, S., Elibol, B., Bulut, H., Meral, I., & Sahin, G. (2021). Angiotensin IV improves spatial memory in streptozotocin‑induced diabetic rats by reducing oxidative stress and altering BDNF levels.

23. Bozkurt, S., Okay, M., & Haznedaroglu, C. I. (2021). First report of t (1; 15)(q21; q11. 2) and t (1; 21)(q21; q11. 2) anomalies in Burkitt Lymphoma.

24.Karataş, M. O., Özdemir, N., Sarıman, M., Günal, S., Ulukaya, E., & Özdemir, İ. (2021). Water-soluble silver (I) complexes with N-donor benzimidazole ligands containing an imidazolium core: Stability and preliminary biological studies. Dalton Transactions50(33), 11596-11603.

25. Ari, F., Napieralski, R., Akgun, O., Magdolen, V., & Ulukaya, E. (2021). Epigenetic modulators combination with chemotherapy in breast cancer cells. Cell Biochemistry and Function39(4), 571-583.

26. Alper, P., Salomatina, O. V., Salakhutdinov, N. F., Ulukaya, E., & Ari, F. (2021). Soloxolone methyl, as a 18βH-glycyrrhetinic acid derivate, may result in endoplasmic reticulum stress to induce apoptosis in breast cancer cells. Bioorganic & Medicinal Chemistry30, 115963.

27. Aydinlik, S., Uvez, A., Kiyan, H. T., Gurel-Gurevin, E., Yilmaz, V. T., Ulukaya, E., & Armutak, E. I. (2021). Palladium (II) complex and thalidomide intercept angiogenic signaling via targeting FAK/Src and Erk/Akt/PLCγ dependent autophagy pathways in human umbilical vein endothelial cells. Microvascular research138, 104229.

28.Ertürk, E., Ari, F., Akgün, O., Ulukaya, E., Küçükali, C. İ., & ZEYBEK, Ş. Ü. (2021). Investigation of the efficacy of paclitaxel on some miRNAs profiles in breast cancer stem cells. Turkish Journal of Biology45(5), 613-623.

 

29. Kuruca, D. S., Dar, K. A., Kapucu, A., & Ozerkan, D. (2021). Clinoptilolite supported feeding reduces excessive iron in thalassemia rat model created with iron loading. Medicine, 10(3), 1031-8.

 

30. Köksal H.Z. Özerkan D. Altuner E.M. Canlı K. (2021). Syntrichia ruraliformis (Besch.) Mans. Hypnum andoi A.J.E.Sm. ve Platyhypnidium riparioides Dixon Etanol Ekstraktlarının HCT116 Hücre Canlılığı Üzerindeki Etkilerinin Spektroskopik Açıdan İncelenmesi. Anatolian Bryology. 7:2, 109-118.

 

31. Kutlu, E., Özgen, İ. T., Bulut, H., Koçyiğit, A., Otçu, H., & Cesur, Y. (2021). Serum irisin levels in central precocious puberty and its variants. The Journal of Clinical Endocrinology & Metabolism106(1), e247-e254.

32. Bulut, H., Yuksel, B., Gul, M., Eren, M., Karatas, E., Kara, N., ... & Binay, B. (2021). Conserved amino acid residues that affect structural stability of candida boidinii formate dehydrogenase. Applied Biochemistry and Biotechnology193(2), 363-376.

33. Duman, T., Akyüz, E., Bulut, H., Koçyiğit, A., Tülek, A., Karataş, E., & Kırpınar, İ. (2021). Investigation of Diagnostic Proteins by 2D Electrophoresis in Major Depression Model Induced by Forced Swim Test in Rats. Protein and Peptide Letters28(2), 195-204.

 

      2020 YILI YAYINLARI

 

 1. Erkisa, M., Ari, F., Ulku, I., Khodadust, R., Yar, Y., Yagci Acar, H., & Ulukaya, E. (2020). Etoposide Loaded SPION‐PNIPAM Nanoparticles Improve the in vitro Therapeutic Outcome on Metastatic Prostate Cancer Cells via Enhanced Apoptosis. Chemistry & Biodiversity17(11), e2000607.

 

2. Erkisa, M., Aydinlik, S., Cevatemre, B., Aztopal, N., Akar, R. O., Celikler, S., ... & Ulukaya, E. (2020). A promising therapeutic combination for metastatic prostate cancer: Chloroquine as autophagy inhibitor and palladium (II) barbiturate complex. Biochimie175, 159-172.

 

3. Mutlu Gençkal, H., Erkisa, M., Alper, P., Sahin, S., Ulukaya, E., & Ari, F. (2020). Mixed ligand complexes of Co (II), Ni (II) and Cu (II) with quercetin and diimine ligands: Synthesis, characterization, anti-cancer and anti-oxidant activity. JBIC Journal of Biological Inorganic Chemistry25(1), 161-177.

4. Yılmaz, I., Akar, O. R., Erkisa, M., Selvi, S., Şengül, A., & Ulukaya, E. (2020). Highly promising antitumor agent of a novel Platinum (II) complex bearing a tetradentate chelating ligand. ACS medicinal chemistry letters11(5), 940-948.

5. Rrustemi, T., Geyik, Ö. G., Özkaya, A. B., Öztürk, T. K., Yüce, Z., & Kılınç, A. (2020). Acrylamide-encapsulated glucose oxidase inhibits breast cancer cell viability. Turkish Journal of Biochemistry45(6), 811-816.

6. Icsel, C., Yilmaz, V. T., Aygun, M., & Ulukaya, E. (2020). Trans-Pd/Pt (II) saccharinate complexes with a phosphine ligand: Synthesis, cytotoxicity and structure-activity relationship. Bioorganic & Medicinal Chemistry Letters30(9), 127077.

7. Latif, A. D., Jernei, T., Podolski-Renić, A., Kuo, C. Y., Vágvölgyi, M., Girst, G., ... & Hunyadi, A. (2020). Protoflavone-chalcone hybrids exhibit enhanced antitumor action through modulating redox balance, depolarizing the mitochondrial membrane, and inhibiting ATR-dependent signaling. Antioxidants9(6), 519.

8. Icsel, C., Yilmaz, V. T., Cevatemre, B., Aygun, M., & Ulukaya, E. (2020). Cytotoxic platinum (II) complexes derived from saccharinate and phosphine ligands: synthesis, structures, DNA cleavage, and oxidative stress-induced apoptosis. JBIC Journal of Biological Inorganic Chemistry25(1), 75-87.

9. Bulut, H., Valjakka, J., Yuksel, B., Yilmazer, B., Turunen, O., & Binay, B. (2020). Effect of metal Ions on the activity of ten NAD-dependent formate dehydrogenases. The Protein Journal39(5), 519-530.

10. Yilmazer, B., Isupov, M. N., De Rose, S. A., Bulut, H., Benninghoff, J. C., Binay, B., & Littlechild, J. A. (2020). Structural insights into the NAD+-dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD+ ternary complex of the Chaetomium thermophilum enzyme. Journal of Structural Biology212(3), 107657.

11. Üyüklü, M., Taş, F., Bolatlı, G., Özçelik, F., Üstünova, S., & Bulut, H. (2020). Sıçanlarda Soğuk Hareketsizlik Stresine Bağlı Gelişen Mide Hasarında S-Allyl Cysteine-in Koruyucu Etkisi.

12. Engin, B., Tanakol, A., Bulut, H., Songür, A., Vehid, H. E., Gökalp, E., ... & Serdaroğlu, S. (2020). Changes in serum TNF‐like weak inducer of apoptosis (TWEAK) levels and Psoriasis Area Severity Index (PASI) scores in plaque psoriasis patients treated with conventional versus anti‐TNF treatments. International Journal of Dermatology59(2), 207-215.

13. Bildaci, Y. D., Çoban, G., Bulut, H., Gürsu, M., Elçioğlu, Ö. C., & Kazancıoğlu, R. (2020). Effects of Keto-Analogs in the Pathologic Findings of Diabetic Nephropathic Rats. Current Status of Renal Replacement Therapy in Turkey.

14. Bozkurt, S., Yarimcan, F., Ayhan, H., Kotan, H., Sezgin, H. T., Çınar, E., ... & Hançer, V. S. (2020). Investigation of PTGS2, MAGE-A3, CALR, KRT19 and TMPRSS4 expressions in HCT116 colon cancer and PC3 prostate cancer cell lines. Genetics & Applications4(2), 37-42.

15. Alagoz, M., Kherad, N., Bozkurt, S., & Yuksel, A. (2020). New mutations in KCNT2 gene causing early infantile epileptic encephalopathy type 57: Case study and literature review. Acta Biochimica Polonica67(3), 431-434.

 

16. Bozkurt, C., Aksoy, B., Aydogdu, S., Bozkurt, S., Cipe, F., Oner, O., ... & Fisgin, T. (2020). Stem cell transplantation for high-risk acute lymphoblastic leukemia in a developing country: a single-center experience. Wiley.

 

17. Büşra, K. Ö. S. E., & BOZKURT, S. (2020). Expression Analysis in the Transcription Level of PTGS2, CALR, MAGE-A3 Genes in Non-Small Cell Lung Cancer. Harran Üniversitesi Tıp Fakültesi Dergisi17(1), 108-112.

 

18. Bozkurt, S., Unal, S., Bayhan, T., Gumruk, F., & Cetin, M. (2020). Rare cytogenetic anomalies in two pediatric patients with acute leukemia.

19. Engin, B., Tanakol, A., Bulut, H., Songür, A., Vehid, H. E., Gökalp, E., ... & Serdaroğlu, S. (2020). Changes in serum TNF‐like weak inducer of apoptosis (TWEAK) levels and Psoriasis Area Severity Index (PASI) scores in plaque psoriasis patients treated with conventional versus anti‐TNF treatments. International Journal of Dermatology59(2), 207-215.

20. Balikci, N., Sarimahmut, M., Ari, F., Aztopal, N., Ozel, M. Z., Ulukaya, E., & Celikler, S. (2020). Toxicity assessment of Hypericum olympicum subsp. olympicum L. on human lymphocytes and breast cancer cell lines.

21. Karakas, D., & Ozpolat, B. (2020). Eukaryotic elongation factor-2 kinase (eEF2K) signaling in tumor and microenvironment as a novel molecular target.

 

      2019 YILI YAYINLARI

 

1. Samli, H., Samli, M., Vatansever, B., Ardicli, S., Aztopal, N., Dincel, D., ... & Balci, F. (2019). Paclitaxel resistance and the role of miRNAs in prostate cancer cell lines. World Journal of Urology37(6), 1117-1126.

2. Akar, R. O., Selvi, S., Ulukaya, E., & Aztopal, N. (2019). Key actors in cancer therapy: epigenetic modifiers. Turkish Journal of Biology43(3), 155-170.

3. Gokmen, Z., Onan, M. E., Deniz, N. G., Karakas, D., & Ulukaya, E. (2019). Synthesis and investigation of cytotoxicity of new N-and S, S-substituted-1, 4-naphthoquinone (1, 4-NQ) derivatives on selected cancer lines. Synthetic Communications49(21), 3008-3016.

4. Karakaş, D., Akar, R. O., Gökmen, Z., Deniz, N. G., & Ulukaya, E. (2019). A novel 1, 4-naphthoquinone-derived compound induces apoptotic cell death in breast cancer cells. Turkish Journal of Biology43(4), 256-263.

5. Karakas, D., Cevatemre, B., Oral, A. Y., Yilmaz, V. T., & Ulukaya, E. (2019). Unfolded Protein Response is Involved in Trans-Platinum (II) Complex-Induced Apoptosis in Prostate Cancer Cells via ROS Accumulation. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents)19(9), 1184-1195.

6. Erkisa, M., Karakas, D., & Ulukaya, E. (2019). Cancer stem cells: root of the evil. Critical Reviews™ in Oncogenesis24(1).

7. Cebi, A., Akgun, E., Celikler, S., Firat, M., Ozel, M. Z., Ulukaya, E., & Ari, F. (2019). Cytotoxic and genotoxic effects of an endemic plant of Turkey Salvia kronenburgii on breast cancer cell lines.

8. Aydinlik, S., Uvez, A., Armutak, E. İ., Dere, E., & Ulukaya, E. (2019). Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism. Annals of Oncology30, v9-v10.

9. Coskun, B., Dizdar, O., Korkmaz, S., Ulukaya, E., & Evrensel, T. (2019). The roles of M30 and M65 in the assessment of treatment response and prognosis in patients with non-small cell lung cancer, who receive neoadjuvant treatment. Contemporary Oncology/Współczesna Onkologia23(4), 208-213.

10. Karakas Zeybek, D., Kahraman, N., Bayraktar, R., Kabil, N., Ulukaya, E., Dere, E., ... & Ozpolat, B. (2019). Identification of microenvironmental regulation and therapeutic targeting of oncogenic eEF2K in pancreatic cancer.

 

11. Icsel, C., Yilmaz, V. T., Cevatemre, B., Aygun, M., & Ulukaya, E. (2019). Structures and anticancer activity of chlorido platinum (II) saccharinate complexes with mono-and dialkylphenylphosphines. Journal of Inorganic Biochemistry195, 39-50.

12. Aydinlik, S., Dere, E., & Ulukaya, E. (2019). Induction of autophagy enhances apoptotic cell death via epidermal growth factor receptor inhibition by canertinib in cervical cancer cells. Biochimica et Biophysica Acta (BBA)-General Subjects1863(5), 903-916.

13. Ayaz, F., Küçükboyacı, N., Gören, N., Çalış, İ., Aydınlık, Ş., Ulukaya, E., ... & Choudhary, M. I. (2019). Bioassay-guided isolation of cytotoxic compounds from Chrysophthalmum montanum (DC.) Boiss. Food and Chemical Toxicology125, 10-20.

14. Alper, P., Erkisa, M., Genckal, H. M., Sahin, S., Ulukaya, E., & Ari, F. (2019). Synthesis, characterization, anticancer and antioxidant activity of new nickel (II) and copper (II) flavonoid complexes. Journal of Molecular Structure1196, 783-792.

15. Karakas, D., Cevatemre, B., Oral, A. Y., Yilmaz, V. T., & Ulukaya, E. (2019). Unfolded Protein Response is Involved in Trans-Platinum (II) Complex-Induced Apoptosis in Prostate Cancer Cells via ROS Accumulation. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents)19(9), 1184-1195.

16. Aydinlik, S., Dere, E., & Ulukaya, E. (2019). Induction of autophagy enhances apoptotic cell death via epidermal growth factor receptor inhibition by canertinib in cervical cancer cells. Biochimica et Biophysica Acta (BBA)-General Subjects1863(5), 903-916.

 

17. Ozyurt, R., Erkasap, N., Ozkurt, M., Erkasap, S., Ulukaya, E., & Dimas, K. (2019). The effect of NOTCH, IL-1 and LEPTIN (NILCO) inhibition in xenograft colorectal cancer.

 

      2018 YILI YAYINLARI

 

1. Bayraktar, R., Ivan, C., Bayraktar, E., Kanlikilicer, P., Kabil, N. N., Kahraman, N., ... & Ozpolat, B. (2018). Dual Suppressive Effect of miR-34a on the FOXM1/eEF2-Kinase Axis Regulates Triple-Negative Breast Cancer Growth and InvasionmiR-34a Regulates TNBC Development Through FOXM1/eEF2K Axis. Clinical Cancer Research24(17), 4225-4241.

2. Yilmaz, V. T., Icsel, C., Aygun, M., Erkisa, M., & Ulukaya, E. (2018). Pd (II) and Pt (II) saccharinate complexes of bis (diphenylphosphino) propane/butane: synthesis, structure, antiproliferative activity and mechanism of action. European Journal of Medicinal Chemistry158, 534-547.

3. Sereti, E., Karagianellou, T., Kotsoni, I., Magouliotis, D., Kamposioras, K., Ulukaya, E., ... & Dimas, K. (2018). Patient Derived Xenografts (PDX) for personalized treatment of pancreatic cancer: emerging allies in the war on a devastating cancer?. Journal of proteomics188, 107-118.

4. Buyukeksi, S. I., Erkisa Genel, M., Şengül, A., Ulukaya, E., & Oral, A. Y. (2018). Structural studies and cytotoxic activity of a new dinuclear coordination compound of palladium (II)-2, 2: 6, 2-terpyridine with rigid dianionic 1, 2, 4-triazole-3-sulfonate linker.

5. Yilmaz, V. T., Icsel, C., Turgut, O. R., Aygun, M., Erkisa, M., Turkdemir, M. H., & Ulukaya, E. (2018). Synthesis, structures and anticancer potentials of platinum (II) saccharinate complexes of tertiary phosphines with phenyl and cyclohexyl groups targeting mitochondria and DNA. European Journal of Medicinal Chemistry155, 609-622.

6. Gurel-Gurevin, E., Kiyan, H. T., Esener, O. B. B., Aydinlik, S., Uvez, A., Ulukaya, E., ... & Armutak, E. I. (2018). Chloroquine used in combination with chemotherapy synergistically suppresses growth and angiogenesis in vitro and in vivo. Anticancer Research38(7), 4011-4020.

7. Zeybek, D. K., Kahraman, N., Bayraktar, R., Kabil, N., Ulukaya, E., Dere, E., ... & Ozpolat, B. (2018). PO-289 Identification of microenvironmental regulation and therapeutic targeting of ongenic EF-2 kinase in pancreatic cancer. ESMO Open3, A340-A341.Cevatemre, B., Dere, E., & Ulukaya, E. (2018). PO-197 A possible link between the mitochondrial gatekeeper pyruvate dehydrogenase enzyme complex and EMT. ESMO Open3, A97.

8. Sereti, E., Tsimplouli, C., Cevatemre, B., Ulukaya, E., Sakellaridis, N., & Dimas, K. (2018). PO-213 Sigma receptors: development of novel therapeutic approaches in pancreatic cancer. ESMO Open3, A310.

9. Aybastıer, Ö., Dawbaa, S., Demir, C., Akgün, O., Ulukaya, E., & Arı, F. (2018). Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis808, 1-9.

10. Cevatemre, B., Dere, E., & Ulukaya, E. (2018). PO-197 A possible link between the mitochondrial gatekeeper pyruvate dehydrogenase enzyme complex and EMT.

11. Bildiren, O., Cevatemre, B., Ay, E. N., Ozen, G., Hepokur, C., Erkisa Genel, M., & Ulukaya, E. (2018). Kalsitriol ve doksorubisin kombinasyonunun MCF7 üzerine olası anti kanser etkilerinin araştırılması.

12. Disoma, C., Erkisa Genel, M., Oran, S. E. Y. H. A. N., Alioglu, I., Ulukaya, E., & Ari, F. E. R. D. A. (2018). Usnea filipendula induces apoptosis in human colon cancer cell lines.

13. Bildiren, Ö., Cevatemre, B., AY, E. N., Güneş, Ö. Z. E. N., Hepokur, C., Erkısa, M., ... & YAYLIM, İ. (2018). An Investigation of Anticancer Effects of Doxorubicin and Calcitriol Combination on MCF-7 Cells. Experimed8(2), 41-46.

14. Buyukeksi, S. I., Erkisa Genel, M., Şengül, A., Ulukaya, E., & Oral, A. Y. (2018). Structural studies and cytotoxic activity of a new dinuclear coordination compound of palladium (II)-2, 2: 6, 2-terpyridine with rigid dianionic 1, 2, 4-triazole-3-sulfonate linker.

15. Icsel, C., Yilmaz, V. T., Aygun, M., Cevatemre, B., Alper, P., & Ulukaya, E. (2018). Palladium (II) and platinum (II) saccharinate complexes with bis (diphenylphosphino) methane/ethane: synthesis, S-phase arrest and ROS-mediated apoptosis in human colon cancer cells. Dalton Transactions47(33), 11397-11410.

16. Cevatemre, B., Erkısa, M., Aztopal, N., Karakas, D., Alper, P., Tsimplouli, C., ... & Ulukaya, E. (2018). A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer. Pharmacological Research129, 500-514.

17. Aztopal, N., Erkisa, M., Ari, F., Dere, E., & Ulukaya, E. (2018). PO-289 Dual inhibition of WNT/β-catenin signalling and histone deacetylation as a new strategy to eliminate breast cancer stem cells by augmentation of apoptosis. ESMO Open3, A133-A134.

18. Aztopal, N., Erkisa, M., Erturk, E., Ulukaya, E., Tokullugil, A. H., & Ari, F. (2018). Valproic acid, a histone deacetylase inhibitor, induces apoptosis in breast cancer stem cells. Chemico-Biological Interactions280, 51-58.

19. Aztopal, N., Erkisa Genel, M., Ari, F., Dere, E., & Ulukaya, E. (2018). Dual inhibition of Wnt/beta-catenin signaling and histone deacetylation as a new strategy to eliminate breast cancer stem cells by augmentation of apoptosis.

 

      2017 YILI YAYINLARI

 

1. Aztopal, N., Karakas, D., Cevatemre, B., Ari, F., Icsel, C., Daidone, M. G., & Ulukaya, E. (2017). A trans-platinum (II) complex induces apoptosis in cancer stem cells of breast cancer. Bioorganic & Medicinal Chemistry25(1), 269-276.

2. Ferda, A. R. İ., Aztopal, N., Erkisa, M., Celikler, S., Sahin, S., & Ulukaya, E. (2017). Nonapoptotic cell death induced by Hypericum species on cancer cells. The European Research Journal3(1), 1-10.

3. Yilmaz, V. T., Icsel, C., Suyunova, F., Aygun, M., Cevatemre, B., & Ulukaya, E. (2017). Synthesis, structures, DNA/protein binding, molecular docking, anticancer activity and ROS generation of Ni (II), Cu (II) and Zn (II) 5, 5-diethylbarbiturate complexes with bis (2-pyridylmethyl) amine and terpyridine. New Journal of Chemistry41(16), 8092-8106.

4. Karakaş, D., Ari, F., & Ulukaya, E. (2017). The MTT viability assay yields strikingly false-positive viabilities although the cells are killed by some plant extracts. Turkish Journal of Biology41(6), 919-925.

5. Cevatemre, B., Dimas, K., Botta, B., & Ulukaya, E. (2017). Pristimerin is a Promising Natural Product against Breast Cancer in vitro and in vivo through Apoptosis and the Blockage of Autophagic Flux. Multidisciplinary Digital Publishing Institute Proceedings1(10), 973.

6. Karakaş, D., Ari, F., & Ulukaya, E. (2017). The MTT viability assay yields strikingly false-positive viabilities although the cells are killed by some plant extracts. Turkish Journal of Biology41(6), 919-925.

7. Aydinlik, S., Erkisa, M., Cevatemre, B., Sarimahmut, M., Dere, E., Ari, F., & Ulukaya, E. (2017). Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line. Biochimica et Biophysica Acta (BBA)-General Subjects1861(2), 49-57.

8. Acilan, C., Cevatemre, B., Adiguzel, Z., Karakas, D., Ulukaya, E., Ribeiro, N., ... & Pessoa, J. C. (2017). Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents. Biochimica et Biophysica Acta (BBA)-General Subjects1861(2), 218-234.

9. Tunc, D., Dere, E., Karakas, D., Cevatemre, B., Yilmaz, V. T., & Ulukaya, E. (2017). Cytotoxic and apoptotic effects of the combination of palladium (II) 5, 5-diethylbarbiturate complex with bis (2-pyridylmethyl) amine and curcumin on non small lung cancer cell lines. Bioorganic & medicinal chemistry25(5), 1717-1723.

10. Kacar, O., Cevatemre, B., Hatipoglu, I., Arda, N., Ulukaya, E., Yilmaz, V. T., & Acilan, C. (2017). The role of cell cycle progression for the apoptosis of cancer cells induced by palladium (II)-saccharinate complexes of terpyridine. Bioorganic & Medicinal Chemistry25(6), 1770-1777.

11. Stasevych, M., Zvarych, V., Lunin, V., Deniz, N. G., Gokmen, Z., Akgun, O., ... & Novikov, V. (2017). Computer-aided prediction and cytotoxicity evaluation of dithiocarbamates of 9, 10-anthracenedione as new anticancer agents. SAR and QSAR in Environmental Research28(5), 355-366.

12. Coskun, D., Erkisa, M., Ulukaya, E., Coskun, M. F., & Ari, F. (2017). Novel 1-(7-ethoxy-1-benzofuran-2-yl) substituted chalcone derivatives: synthesis, characterization and anticancer activity. European journal of medicinal chemistry136, 212-222.

13. Cetin, Y., Adiguzel, Z., Polat, H. U., Akkoc, T., Tas, A., Cevatemre, B., ... & Acilan, C. (2017). A palladium (II)–saccharinate complex of terpyridine exerts higher anticancer potency and less toxicity than cisplatin in a mouse allograft model. Anti-Cancer Drugs28(8), 898-910.

14. Duman, F. D., Erkisa, M., Khodadust, R., Ari, F., Ulukaya, E., & Acar, H. Y. (2017). Folic acid-conjugated cationic Ag2S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells. Nanomedicine12(19), 2319-2333.

15. Içsel, C., Ulukaya, E., Yilmaz, V. T., & Dimas, K. (2017). U.S. Patent No. 9,839,643. Washington, DC: U.S. Patent and Trademark Office.

16. Asmat, S., Husain, Q., & Azam, A. (2017). Lipase immobilization on facile synthesized polyaniline-coated silver-functionalized graphene oxide nanocomposites as novel biocatalysts: stability and activity insights. RSC advances7(9), 5019-5029.